Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model.
نویسندگان
چکیده
Ciprofloxacin, gatifloxacin, and levofloxacin were evaluated for their abilities to prevent mortality in hamsters infected with a lethal inoculum of Leptospira interrogans serovar Portlandvere. Each agent produced a statistically significant survival advantage compared to no treatment and demonstrated survival similar to that seen with doxycycline therapy.
منابع مشابه
Efficacy of Fluoroquinolones against Leptospira in a Hamster Model 1 2
45 Ciprofloxacin, gatifloxacin, and levofloxacin were evaluated for their ability to prevent 46 mortality in hamsters infected with a lethal inoculum of Leptospira interrogans serovar 47 Portlandvere. Each agent produced a statistically significant survival advantage when 48 compared to no treatment and demonstrated survival similar to that seen with 49 doxycycline therapy. 50 51 52 53 54 55 56...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 51 7 شماره
صفحات -
تاریخ انتشار 2007